Basal ganglia - blood supply and disorders

senoyaga's version from 2016-01-30 16:28


Question Answer
the blood supply to the striatum is...from penetrating branches of anterior and middle cerebral a.a., specifically medial/lateral striate or lenticulostriate
blood supply to globus pallidus is...from anterior choroidal artery.
blood supply to subthalamic nucleus and substantia nigra is...from penetrating branches of posterior cerebral artery
parkinson's disease is characterized by...rigidity and difficulty moving, fewer slower movements, and resting tremor
the most common basal ganglia disorder is...Parkinson's disease
Parkinson's disease leads to...degeneration of substantia nigra and reduced production of dopamine
with parkinson's disease output from where is increased?globus pallidus
with parkinson's disease, output from where is decreased?thalamus and cortex
rigidity, increased tone, slow reduced movements, bradykinesia/hypokinesia, stooped posture, resting tremor are all symptoms of....Parkinson's disease
Parkinson's disease is treated by...administering the precursor to dopamine, L-Dopa to specific locations or injection of stem cells to replace damaged cells in the basal ganglia
disorders of the basal ganglia result in what movement abnormalities?involuntary movements, problems initiating movements, and disturbances with muscle tone
which basal ganglia disorder is characterized by rhythmic, oscillatory, involuntary movementstremors
which basal ganglia disorder is characterized by uncoordinated swinging of the limbs and jerky movements....ballismus
what basal ganglia disorder is characterized by nearly continuous, rapid movements of the face, tongue, or limbs?chorea
which basal ganglia disorder is characterized by slow, writhing movements, most pronounced in hands and fingers like "pill rolling"athetosis
which basal ganglia disorder is characterized by continuous rapid movements of the face and limbs (dance-like)huntington's disease
Huntington's disease is...degeneration of the caudate nucleus resulting in involuntary movements
in huntington's disease there is less output from...striatum which causes increase inhibition of globus pallidus
in huntington's disease there is a decrease in....subthalamic activity (indirect pathway)
in huntington's disease there is increased output of...thalamus and cortex (hyperkinesia)
which basal ganglia disorder is characterized by wild flailing movement of the arm and leg of one side...hemiballismus
hemiballismus is...a stroke of posterior perforating arteries or lesion in contralateral subthalamic nucleus which causes decreased output from subthalamic nucleus and leads to inhibitio of GP
hemiballismus increases output of...thalamus and cortex
effective treatments for disorders of the basal ganglia are...pallidotomy or thalamotomy, which is disconnecting the pathway that's affected or deep brain stimulation, which basically replaces the abnormal brain activity