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Autoantibodies

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plusmarek's version from 2016-02-20 22:29

Section

Question Answer
Anti-ACh receptorMysathenia Gravis
Anti-basement membraneGoodpasture syndrome
Anticardiolipin, lupus anticoagulantSLE, antiphospholipid syndrome [can cause false (+) syphilis]
AnticentromereCREST syndrome (limited scleroderma)
Anti-desmoglein (anti-desmosome)Pemphigus Vulgaris
Anti-dsDNA, anti-SmithSLE
Anti-glutamic acid decarboxylase (GAD-65)Type 1 DM
AntihemidesmosomeBullous pemphigoid
Anti-histoneDrug-induced lupus
Anti-Jo, anti-SRP, anti-Mi-2Polymyositis, dermatomyositis
Antimicrosomial, antithyroglobulinHashimoto thyroiditis
AntimitochondrialPrimary biliary cirrhosis
Antinuclear (ANA)SLE, non-specific
Antiparietal cellPernicous anemia
Antiphospholipase A2 receptorPrimary membranous nephropathy
Anti-Scl-70 (anti-DNA topoisomerase I)Scleroderma (diffuse)
Anti-smooth muscleAutoimmune hepatitis type 1
Anti-SSA, SSB (anti-Ro, anti-La)Sjogren Syndrome
Anti-TSH receptorGraves disease
Anti-U1 RNP (ribonucleoprotein)Mixed connective tissue disease
Voltage gated calcium channel AbLambert-Eaton syndrome
IgA anti-endomysial, IgA anti-tissue transglutaminaseCeliac disease
MPO-ANCA (P-ANCA)Microscopic polyangitis, eosinophilic granulomatosis with polyangitis (Churg-Strauss)
PR3-ANCA (C-ANCA)Granulomatosis with polyangitis (Wegener)
Rheumatoid Factor (IgM Ab vs IgG Fc region); anti-CCP (more specific)Rhematoid arthritis
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