Create
Learn
Share

Antidiabetic Drugs

rename
depedoju's version from 2017-12-01 00:10

Section 1

Question Answer
SulfonylreasGlyburide
Megletinide AnaloguesRepaglinide
Thiazolidinediones (TZD's)Pioglitazone
BiguanidesMetformin
Alpha Glucosidase InhibitorsAcarbose
memorize

Section 2

Question Answer
Reduce production of glocose from liver and increase insulin sensitivityThiazolidinediones (TZD's)
Triggers Beta cells to release insulin thereby increasing meal related insulinMegletinide Analogues
Hold 48 hours before and after contrast die and surgery (Must swallow whole)Biguanides
Take with first bite of each mealAlpha Glucosidase Inhibitors
Take 30 minutes before meals (Swallow tablet whole)Sulfonylreas
memorize

Section 3

Question Answer
Side effects include flatulence, diarrhea, abdominal discomfortAlpha Glucosidase Inhibitors
1-30 minutes before mealsMegletinide Analogues
decrease glucose production from liver thereby reducing fasting plasma glucose release and improves receptor sensitivity.Biguanides
Stimulate insulin secretion and increase cell receptor sensitivitySulfonylreas
Reduce oral contraceptive effectThiazolidinediones (TZD's)
memorize

Section 4

Question Answer
Thiazolidinediones (TZD's)Side effects can include M.I. and CHF
SulfonylreasInteractions with: Alcohol, Beta blockers, NSAID's, Diuretics, antibiotics etc.
BiguanidesCan cause kidney failure and lead to lactic acidosis
Megletinide AnaloguesRapid absorption/short acting
Alpha Glucosidase InhibitorsDelays absorption of carbohydrates in small intestines
memorize