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Antidepressents

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nelso418's version from 2016-12-11 22:11

Section

Question Answer
DesipramineNRI
NortriptylineNRI
ProtriptylineNRI
AmoxapineNRI - post-synaptic 5-HT2 antag, D2 receptor antag - antipsychotic action
MaprotilineNRI
CitalopramSSRI
EscitalopramSSRI - most selective
FluoxetineSSRI - once weekly dose, Tx: Sarafem - PMDD. Tx: OCD, PTSD
FluvoxamineSSRI - OCD, SAD
ParoxetineSSRI - "worst of the SSRIs"
SertralineSSRI - OCD, PMDD
AmitriptylineSNRI - neuropathic pain
ClomipramineSNRI - OCD
DoxepinSNRI
ImipramineSNRI - enuresis
TrimipramineSNRI
Desvenlafaxinenon-TCA SNRI, low doses SA block, Mod. doses SA & NE, High doses - SA, NE & DA
Duloxetinenon-TCA SNRI - diabetic neuropathy, stress incontinence
Levomilnaciprannon-TCA SNRI - depression
Milnacipran non-TCA SNRI - neuropathic pain
Venlafaxinenon-TCA SNRI, low doses SA block, Mod. doses SA & NE, High doses - SA, NE & DA
BupropionNDRI - smoking cessation - blocks DA reuptake, lowers seizure threshold
TrazodoneSARI - adrenergic pre-synaptic 5HT-2A antag, post-synaptic 5-HT2 antag - antipsychotic actions
VilazodoneSARI - adrenergic pre-synaptic 5HT-2A antag, post-synaptic 5-HT2 antag - antipsychotic actions. Significant CYP3A4 metabolism
VortioxetineSARI - adrenergic pre-synaptic 5HT-2A antag, post-synaptic 5-HT2 antag - antipsychotic actions. Significant CYP3A4 metabolism
MirtazapineNaSSA - pre-synaptic 5HT2A , pre-synaptic alpha2 antag, post-synaptic 5-HT antag; aids insomnia, aids appetite
AripiprazoleSDAM - antipsychotic
BrexiprazoleSDAM - antipsychotic
PhenelzineMAOI
TranylcypromineMAOI
SelegilineMAOI - transdermal patch, no dietary restrictions for low dose 6mg/24 hours
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