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Antidepressant, Antipsychotic, Antianxiety Drugs
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lekhoa 's2012-11-12 05:11
Antidepressant (Don't use with MAO)
Generic Name Brand Name Classification fluvoxamine Luvox Serotonin Recycle inhibitor Antidepressant fluoxetine Prozac, Sarafem Serotonin Recycle inhibitor Antidepressant paroxetine hydrochloride Paxil Serotonin Recycle inhibitor Antidepressant sertraline hydrochloride Zoloft Serotonin Recycle inhibitor Antidepressant citalopram Celexa Serotonin Recycle inhibitor Antidepressant escitalopram Lexapro Serotonin Recycle inhibitor Antidepressant paroxetine mesylate Asimia Serotonin Recycle inhibitor Antidepressant venlafaxine Effexor XR Serotonin Recycle inhibitor Antidepressant
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Serotonin Agoinist Migraine (vasodilation)
Generic Name Brand Name Classification sumatriptan succinate Imitrex Serotonin Agoinist Migraine (vasodilation)
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Antidepressant (Don't use with MAO)
Generic Name Brand Name Classification imipramine Tofranil, Janimine Tricyclic Reuptake Inhibit Antidepressant desipramine Norpramin, Pertofrane Tricyclic Reuptake Inhibit Antidepressant amitriptyline Elavil, Apo-amitriptyline Tricyclic Reuptake Inhibit Antidepressant nortriptyline Aventyl Tricyclic Reuptake Inhibit Antidepressant doxepin Adapin , Sinequan Tricyclic Reuptake Inhibit Antidepressant amoxapine Ascendin Tricyclic Reuptake Inhibit Antidepressant
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Antidepressant
Generic Name Brand Name Classification mirtazapine Remeron Tetracyclic Antidepressant
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Heterocyclic Antidepressant
Generic Name Brand Name Classification trazodone Desyrel Heterocyclic Antidepressant maprotiline Ludiomil Heterocyclic Antidepressant nefazadone Serzone Heterocyclic Antidepressant, Severe hepatic failure
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MAO
Generic Name Brand Name Classification phenelzine Nardil Antidepressant, MAO
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Unclassified Antidepressant
Generic Name Brand Name Classification bupropion Wellbutrin, Wellbutrin SR, Zyban Unclassified
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Antianxiety
Generic Name Brand Name Classification alprazolam Xanax Antianxiety buspirone Buspar Antianxiety (Damage hepatic-renal) oxazepam Serax Antianxiety lorazepam Ativan, Apo-lorazepam Antianxiety(use in permature awakening)
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Insomnia & Sleep Disorders(Contra: sedation drugs,barbiturate,antihistamine,ethanol)
Generic Name Brand Name Classification bromazepam Lectopam Insomnia & Sleep Disorders temazepam Restoril Insomnia & Sleep Disorders(use in permature awakening) triazolam Halcion Insomnia & Sleep Disorders zolpidem Ambien Insomnia & Sleep Disorders
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Therapy of Seizure
Generic Name Brand Name Classification carbamazepine Tegretol XR, Cabatrol Anticonvulsant phenytoin sodium Dilantin Infatab, Dilantin-125 Anticonvulsant fosphenytoin Cerebyx Anticonvulsant gabapentin Neurontin Anticonvulsant vigabatrin Sabril Anticonvulsant tiagabine Gabatril Anticonvulsant valproic acid Depakene Anticonvulsant(extremely sedating) lamotrigine Lamictal Anticonvulsant(Severe skin rash) diazepam Valium, Apo-diazepam Anticonvulsant
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Question Answer Column 3 methylphenidate Ritalin, Concerta (methyphenidate XR) Epilepticus or Attention Deficit Hyperactivity Disorder (ADHD)
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Parkinson
Generic Name Brand Name Classification l-dopa (levodopa) Dopar, Larodopar increase dopamine (park) levodopa with carbidopa Sinement increase dopamine (park) bromocriptine Parlodel, Ergoset increase dopamine (park)(Sotage < Room Temperature) tolcapone Tasmar, Mirapex increase dopamine (park)(Severe liver injury) selegiline Eldepryl, Carbex increase dopamine (park)
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Parkinson (Decrease Acetylcholine)
Question Answer Column 3 procyclidine Kemadrin Decrease Acetylcholine (park) biperiden Akineton Decrease Acetylcholine (park) amantadine HCl Symmetrel Decrease Acetylcholine (park)
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Alzheimer (inhibitor of acetylcholinesterase which break down acetylcholine )
Generic Name Brand Name Classification tacrine Cognex increase acetylcholine (alzheimer) donezepil Aricept increase acetylcholine (alzheimer)
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Schizophrenia (increase dopamine in Striatum)(block dopa recept)=> dopa useless
Generic Name Brand Name Classification chlorpromazine Thorazine, Largactil Schizophrenia thioridazine Mellaril Schizophrenia haloperidol Haldol Schizophrenia olanzapine Zyprexa Schizophrenia clozapine Clozaril Schizophrenia fluphenazine Permitil, Prolixin Schizophrenia loxapine Loxitane Schizophrenia quetiapine Seroquel Schizophrenia
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Nonsteroidal Anti-Inflammatory Drugs
Generic Name Brand Name Classification aspirin(acetylsalicylic acid Various COX1 ibuprofen IBU, Motrin, Advil, Provil COX1 & COX2 ketoprofen Actron, Oruvail, Orvdis 5*ibuprofen COX1&2 flurbiprofen Ansaid, Ocufen can use in eyes indomethacin Indocin against COX1 ketorolac Toradol, Aculan OPHT inhibitor COX-1, Damage renal sulindac Clinoril Inhibitor COX1&2 nabumetone Relafen Nonsteroidal Anti-Inflammatory naproxen Naprosyn, EC-Naprosyn, Naprelan Nonsteroidal Anti-Inflammatory naproxen sodium Anaprox, Naprelan, Aleve(OTC) Nonsteroidal Anti-Inflammatory
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Nonsteroidal Pain Relievers
Generic Name Brand Name Classification acetaminophen Tylenol large or frequent dosing extremely damage liver
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Narcotic Analgesic
Generic Name Brand Name Classification morphine sulfate Morph Sul, MSIR, RMS, Roxanol, C-II, strong sedative meperidine hydrochloride Demerol C-II,euphoric,addictivable hydromorphone hydrochloride Dilaudid C-II,great for addiction,euphoria,abuse fentanyl (base) Actiq C-II fentanyl citrate Duragesic transdermal patch C-II methadone Dolophine C-II,not euphoria,not addictive codeine and acetaminophen Tylenol #1,#2,#3,#4 C-III hydrocodone and acetaminophen Anexia, Lorcet, Vicodin Controll substance, large dose=> lose liver oxycodone Percocet, Percodan C-II
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Narcotic Analgesic(low abuse potential)
Generic Name Brand Name Classification propoxyphene hydrochloride with aspirin Darvon, Doloxen, Progesic Controlled Substance propoxyphene napsylate Darvon-N C-II
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Narcotic Analgesic(Partial Agonist and Antagonist)
Generic Name Brand Name Classification buprenorphine Stadol, Stadol NS Controlled substance(withdrawal symptoms) (partial anta) pentazocine Talwin C-IV (partial anta) naloxone Narcan very short acting,and reversal effects seen in a matter of minutes Antagonist nalmefene Revex Antagonist naltrexone Revia Antagonist
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Recall
Generic Name Brand Name Classification β1 receptor increase heartrate and force contraction of the hear muscle β1 receptor blocker(antagonist) decrease heartrate and heart ouput decrease blood pressure and increase tissue perfusion. slowed cardiac conduction rate,decrease arrhythmias, decrease renin(vasocontriction)
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blockade of B1 and/ or B2 may interfere with blood sugar, blockade of b2 receptor may cause bronchoconstriction
Question Answer Beta receptor agonist ??? tissue perfusion, force of the heart contraction, increase blood sugar, blood pressure and cardiac output (useful in hypovolemia and asthma ) contraindicated with diabete Alpha receptor antagonist decrease peripheral vasoconstriction, lowering blood pressure and cardiac afterload (hypertension), adverse effect: postural hypotension Alpha receptor agonist emergency situations of shock, intranasally as decongestant, adverse effect: increase blood pressure Alpha2 receptor Agonist therapy of hypertension, therapy of opiate addiction
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Muscarinic Antagonists (antiparasympathetic): block parasympathetic effects => sympathetic effects are seen
Recall
Question Answer Calcium Channel Blockers 1/ Vascular smooth muscle, relax the smooth muscle of arteries and cause vasodilation => useful as antihypertensive and antianginal. 2/ decrease heartrate and cardiac excitability,
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useful as antiarrhythmics and antihypertensive, antiangina 3/ sympatholytic effect.
Effects of Calcium Channel Blockers is flushing, dizziness, constipation, nausea.
Use for treatment of bone pain associated with cyclosporine (Transplant patient)
Beta Receptor Antagonist
Generic Name Brand Name Classification propranolol Inderal, Inderal SA block β1 and β2 equally, contraindicated for diabetic and asthma atenolol Tenormin selective β1 adrenergic blocker metoprolol succinate Toprol -XL selective β1 adrenergic blocker metoprolol tartrate Lopressor selective β1 adrenergic blocker
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Beta Receptor Agonist
Generic Name Brand Name Classification isoproterenol Isuprel stimulate both β1 & 2 receptor, increase blood pressure, cardiac output, tissue perfusion, contraindicate in diabetic, use in asthma
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Alpha Receptor Antagonist
Generic Name Brand Name Classification doxazosin mesylate Cardura antagonist a1 receptor, use in prostatic hypertrophy, may cause postural hypotension,store < BRT prazosin hydrochloride Minipress antagonist a1 receptor, use in hypertension, may cause postural hypotension terazosin Hytrin similar with doxazosin and prazosin
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Alpha Receptor Agonist
Generic Name Brand Name Classification norepinephrine Levophed stimulate a1 receptor, increase blood pressure, also stimulate b1 so heart renin blood sugar are affected epinephrine Adrenalin stimulate 4 kind of adrenergic receptors similar to norepinephrine phenylephrine Neo Synephrine nasal spray, hypotensive crisis only tetrahydrozoline ophthalmic drops, may aggravate prostatic hypertrophy. oxymetazoline nasal spray, stimulate a1 and a2 , will aggravate hypertension or BPH
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Alpha2 receptor Agonist
Generic Name Brand Name Classification clonidine hydrochloride Catapres antihypertension, inhibition of norepinephrine, increase platelet aggregation, abrupt withdrawal may lead to hypertensive crisis alpha methyl dopa (a-methyldopa) Aldomet may cause rash,liver damage, breast larger, joint pain, use for hypertension
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Muscarinic Antagonists (antiparasympathetic)
Generic Name Brand Name Classification atropine Sal-Tropine, Atropisol (opht) Therapy of heart block, hyperactive sinus reflex, antidote for muscarinic poisoning, normalize cardiac function
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Calcium Channel Blockers
Generic Name Brand Name Classification nifedipine Adalat, Procardia, Procardia XL negligible effect on cardiac tissue, no sympathetic effect nicardipine Cardene no effect on cardiac tissue, use in congestive heart failure nimodipine Nimotop cerebral arterioles, not take with food or parenteral injection amplodipine Norvasc, amplodipine-1, Lotrel angina, hypertension
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effect on cardiac function
Question Answer Column 3 verapamil Calan, Isoptin, Verelan, Verelan SR, Verelan PM (chronotherapeutic), CoVera HS hypertension, atrial arrhythimias, angina diltiazem Cardizem, Dilacor, Tiazac, Tiamate, Cartia XT, Taztia XT, Diltiazem HCL , Cardizem SR - CD, Dilacor XR angina, may cause fatal arrhythmias, arrhythmias, vasodilator, hypertension
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Important
Generic Name Brand Name Classification adverse effects hypotension, rash, renal damage, contraindicated in pregnacy
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Inhibitors of Angiotensin-Converting Enzyme (ACE Inhibitors)
Generic Name Brand Name Classification benazepril Lotensin (ACE Inhibitors) hyportension captopril Capoten (ACE Inhibitors) use in hypertension, CHF enalapril Vasotec (ACE Inhibitors) use in heart failure, hypertension fosinopril sodium Monopril (ACE Inhibitors) lisinopril Prinivil, Zestril combined (Prinzide, Zestoretic) (ACE Inhibitors)
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Angiotensin II Receptor Blockers
Generic Name Brand Name Classification candesartan cilexetil Atacand Angiotensin II Receptor Blockers irbesartan Avapro, combine(avalide ,with HCTZ) Angiotensin II Receptor Blockers telmisartan Micardis Angiotensin II Receptor Blockers valsartan Diovan Angiotensin II Receptor Blockers losartan potassium Cozaar, Hyzaar (with HCTZ) Angiotensin II Receptor Blockers
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Direct Vasodilators
Generic Name Brand Name Classification hydralazine Apresoline, Apresazide ( with HCTZ) Direct Vasodilators diazoxide Hyperstat IV Direct Vasodilators
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Venodilators (Nitrates)
Generic Name Brand Name Classification nitroglycerin Nitrol, Nitro-BID, Nitrostat, Nitrostat Sub (sublingual), Nitro-Dur, Nitro Trans, Deponit, Nitro Disc, Minitran TDS (patch) Venodilators (Nitrates) isosorbide mononitrate Ismo, Monoket, Imdur Venodilators (Nitrates) isosorbide dinitrate Isordil Venodilators (Nitrates) sodium nitroprusside Nitropress, Nitroprussin Venodilators (Nitrates)
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Inotropic Agents Cardiac Glycosides (very narrow therapy window, early toxic effects are slow heart rate (bradycardia), later toxic effects(tachycardia)
Generic Name Brand Name Classification digoxin Lanoxicaps, Lanoxin Cardiac Glycosides (drink and inject) digitoxin Crystodigin Cardiac Glycosides (drink and inject) dopamine N/A Cardiac Glycosides (inject) dobutamine Dobutrex Cardiac Glycosides (inject)
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Inotropic Agents, Phosphodiesterase Inhibitors (Methylxanthines & Bipyridines)
Generic Name Brand Name Classification amrinone Inocor IV Bipyridines increase levels of cAMP milrinone Primacor Bipyridines increase levels of cAMP
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* Methylxanthines
Sodium Channel Blockers ( also local anesthetics, uesd to block pain, antiarrhythmias )
Generic Name Brand Name Classification lidocaine Xylocaine Sodium Channel Blockers quinidine Cardioquin, Quinaglute Dura Sodium Channel Blockers disopyramide Norpace Sodium Channel Blockers (anticholinergic)
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Decrease Fluid Volume (Loop Diuretics)
Generic Name Brand Name Classification torsemide Demedex Loop Diuretics bumetanide Bumex Loop Diuretics furosemide Lasix, Myrosemide Loop Diuretics chlorothiazide Diuril Thiazide Diuretics hydrochlorothiazide Esidrex, Ezide, Oretic Thiazide Diuretics acetazolamide Diamox carbonic anhydrase inhibitor amiloride hydrochloride Midamor potassium-sparing diuretics spironolactone Aldactone potassium-sparing diuretics triamterene and hydrochlorothiazide Dyazide, Maxzide potassium-sparing diuretics
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Drug Used in the Therapy of Inappropriate ADH Secretion (SIADH) Syndrome
Generic Name Brand Name Classification demeclocycline Declomycin antidiuretic hormone (ADH) antagonist.
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Drugs Used to Reduce Blood Cholesterol
Generic Name Brand Name Classification cholestyramine Prevalite, Questran Bile Binding Resins
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2012-11-12 05:11
