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Antibodies and diseases

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medmaestro's version from 2015-11-17 09:17

Section

Cell or Organ Specific Auto immunity-1
Question Answer
Acetylcholine receptorMyasthenia gravis
ActinChronic active hepatitis, primary bilary cirrhosis
Adenine nucleotide translator(ANT)Dilated cardiomyopathy, myocarditis
AdrenoreceptorDilated cardiomyopathy
Aromatic L amino acid deccarboxylaseAutoimmune polyendocrine syndrome type 1(APS1)
Asialoglycoprotein receptorAutoimmune hepatitis
Bactericidal/permeability increasing protein (Bpi)Cystic fibrosis vasculitides
Calcium sensing receptorAcquired hypoparathyoidism
Cholesterol side chain cleavage enzyme(CYPlla)Autoimmune poly glandular syndrome 1
Collagen type IV-3-chainGoodpasture syndrome
Cytochrome P450 2D6(CYP2D6)Autoimmune hepatitis
DesminCrohn disease, coronary artery disease
Desmoglein 1Pemphigus foliaceus
Desmoglein 3Pemphigus vulgaris
F-actinAutoimmune hepatitis
GM gangliosidesGullain Barre syndrome
Glutamate decaroxylase(GAD65)Type 1 diabetes, stiff man syndrome
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Cell or Organ Specific Auto immunity-2
Question Answer
Glutamate receptor(GLUR) Rasmussen encephalitis
H/K ATPaseAutoimmune gastritis
17-Hydroxylase(CYP17)Autoimmune poly glandular syndrome-1
21-Hydroxylase (CYP21)Addison disease
IA-2(ICA512)type ! diabetes
InsulinType 1 diabetes, Insulin hypoglycemic syndrome(Hirata disease)
Insulin receptorType B insulin resistance, acanthosis, systemic lupus, erythematosus(SLE)
Intrinsic factor type 1Pernicious anemia
Leukocyte function –associated antigen(LFA-1)Treatment resistant Lyme arthritis
Myelin associated glycoprotein(MAG)Polyneuropathy
Myelin basic proteinMultiple sclerosis, demyelinating diseases
Myelin oligodendrocyte glycoprotein (MOG)Multiple sclerosis
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Cell or Organ Specific Auto immunity-3
Question Answer
MyosinRheumatic fever
P80ColinAtopic dermatitis
Pyruvate dehydrogenase complex E2(PDC E2)Primary bilary cirrhosis
Sodium Iodide symporter(NIS)Graves’ disease, auto immune hypothyroidism
SOX 10Vitiligo
Thyroid and eye muscle shared proteinThyroid associated ophthalmology
ThyroglobulinAutoimmune thyroiditis
Thyroid peroxidaseAutoimmune Hashimoto thyroiditis
Throtropin receptorGraves’ disease
Tissue transglutaaminaseCeliac disease
Transcription coactivator p75Atopic dermatitis
Tryptophan hydroxylaseAutoimmune polyglandular syndrome 1
TyrosinaseVitilago,metalystic melanoma
Tyrosine hydroxylase: Autoimmune polyglandular syndrome 1
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Systemic Autoimmunity
Question Answer
ACTHACTH deficiency
Aminoacyl-tRNA histidyl synthetaseMyositis,dermatomyositis
Aminoacyl-tRNA synthetase(several)Polymyositis,dermatomyositis
CardiolipinSLE Antiphospholipid syndrome
Carbonic anhydrase IISLE, Sjogren syndrome,systemic sclerosis
Ku nucleoproteinConnective tissue syndrome
La Phosphoprotein(LaSSB)Sjogren syndrome
Collagen (multiple types)Rheumatoid arthritis(RA),SLE,Progressive Systemic sclerosis
Centromere associated proteinsSystemic sclerosis
DNA dependent nucleosine stimulated ATPaseDermatomyositis
FibrillarinScleroderma
FibronectinSLE, RA, morphea
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Systemic Autoimmunity
Question Answer
Glucose 6 phosphate isomeraseRA
2 -Glycoprotein I(B2GPI)Primary antiphospholipid syndrome
Golgin(95,97,160,180)Sjogren syndrome ,SLE, RA
Heat shock ProteinVarious immune related disorders
Hemisdesmosomal protein 180Bullous pemphigoid,herpes gestationis,Cicatrical phemphigoid
Histone H2A H2BDNASLE
IgE receptorChronic Idiopathic urticaria
KeratinRA
Ku DNA protein KinaseSLE
MyeloperoxidaeNecrotizing and crescentic glomerulonephritis (NCGN)Systemic Vasculitis
Proteinase 3(PR3)Wegner granulomatosis,Churg Strauss syndrome
RNA polymerase I-III(RNP)Systemic sclerosis ,SLR
Signal recognition protein(SRP54)Polymyositis
Topoisomerase I(Scl-70)Scleroderma,Raynaud syndrome
TublinChronic liver disease, visceral leishmaniasis
VimentinSystemic autoimmune disease
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Plasma Protein and Cytokine Autoimmunity
Question Answer
Cl inhibitorAutoimmune Cl deficiency
CLqSLE,membrane proliferative glomerulonephritis (MPGN)
Cytokines (IL-1,IL-6IL-10,LIF)RA, Systemic Sclerosis, normal subjects
Factor II, factor V,factor VII,factor VIII,factor IX factor X,factor XI,thrombin VwfProlonged coagulation time
Glycoprotein IIb/III and Ib/IXAutoimmune thrombocytopenia purpura
IgAImmunopdecficency associated with SLE,Perinicious anemia,thyroiditis,Sjogren’s syndrome and chronic active hepatitis
Oxidized LDL(oxLDL)Atherosclerosis
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Cancer and Paraneoplastic Autoimmunity
Question Answer
AmhiphysianNeuropathy ,small cell lung cancer
Cyclin B1Hepatocellular carcinoma
DNA topoisomerase IILiver cancer
DesmoplakinPareneoplastic pemphigus
GephyrinPareneoplastic stiff man syndrome
Hu proteinsParaneoplastic encephalomyelitis
Neuronal nicotinic acetylcholine receptorsubacute autonomic neuropathy,cancer
P53Cancer,SLE
P62(IGF_IImRNA-binding protein)Hepatocellular carcinoma(China)
RecoverinCancer associated retinopathy
Ri proteinParaneoplastic opscolonus myocolonus ataxia
IV SpectrinLower motor neuron syndrome
SynaptotagminLambert-Eaton myasthenic syndrome
Voltage gated calcium channelsLambert-Eaton mysthenic syndrome
Yo ProteinParaneoplastic cerebellar degeneration
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