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Antibiotics

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waveurflag's version from 2018-10-21 22:35

Section 1

Question Answer
VancomycinGlycopeptide; works on gram positve, can cause nephrotoxicity, RED MAN syndrome, covers MRSA
Polymyxin Glycopeptide; gram negative, causes nephrotoxicity, covers pseudomonas
Telavancin, Daptomycin, OritavancinGlycopeptide; covers gram positive BUT covers pseudomonas and MRSA
Fosfomycin Glycopeptide; gram positive AND negative, ONLY for UTIs now, can cause headaches and GI distrubance
memorize

Section 2

Question Answer
Penicillin VKBeta-Lactam; gram positive, ONLY PO
Penicillin GBeta-Lactam; gram positive, ONLY IV/IM
AmoxicillinBeta-Lactam; gram positive, ONLY PO, used to treat AOM :)
AmpicillinBeta-Lactam; gram positive, PO or IV
cillins love enterococci
AztreonamMonobactam; gram negative, DO NOT GIVE with ceftazidime, IV
MeropenemCarbapenem; gram positive AND negative, covers pseudomonas
ErtapenemCarbapenem; gram positive AND negative and anaerobes, NOT enterococcus,
Cefazolin1st gen Cephalosporin; gram positive AND negative,
Cephalexin1st gen Cephalosporin; gram positive AND negative, ONLY PO
Cefuroxime2nd gen Cephalosporin; gram positive AND negative and anaerobes, ONLY IV or PO
Cefoxitin2nd gen Cephalosporin; gram positive AND negative and anaerobes
Cefaclor2nd gen Cephalosporin; gram positive AND negative and anaerobes, ONLY PO
Ceftriaxone3rd gen Cephalosporin; gram positive AND negative, ADVERSE RXN: hyperbilirubinemia, jaundice, calcium-binding, encephalopathy in neonates
Cefpodoxime3rd gen Cephalosporin; gram positive AND negative, ONLY PO
Cefixime3rd gen Cephalosporin; gram positive AND negative, ONLY PO (same as other one)
Cefepime 4th gen Cephalosporin; gram positive AND negative, covers pseudomonas, CAUSES encephalitis
Ceftaroline5th gen Cephalosporin; gram positive AND negative, covers MRSA
Cephalosporins don't likeenterococci
memorize

Section 3

Question Answer
Aminoglycosides inhibit 30S, gram negative, cover pseudomonas, end in -mycin (Amikacin, tobramycin, gentamicin), all require TDM, CAUSE nephro- and ototoxicity
Doxycycline, MinocyclineTetracyclines, gram positive, cover MRSA, don't like enterococci, ADVERSE RXNS: hepatotoxcity, photosensitivity, GI upset, stain teeth, chelation of cations, DON'T give to older ppl and pregnant women
Tetracycline Tetracycline, gram positive and some negative GNRs, not really used because a LOT of adverse events
LinezolidInhibits 50s, Oxazolidonone; gram positive, covers MRSA, CAUTION, may cause thrombocytopenia
Tigecycline Glycycline; gram EVERYTHING, guess what tho? It can KILL you.
Azithromycin, ClarithromycinInhibits 60S, Macrolides; gram positive, HATES enterococci, IV and PO available, can CAUSE QTC prolongation, GI upset
ClindamycinInhibits 60S, Lincosamide; gram positive AND anaeorobes, HATES enterococci, covers MRSA, IV or PO
memorize

Section 4

Question Answer
Ciprofloxacin, LevofloxacinFluoroquinolone; gram negative, covers pseudomonas, CAUSE chelation of cations, QTC prologation, don't wanna give to old ppl
MoxifloxacinFluoroquinolone; anaerobes, ONLY for UTIs
SMX/TMPcover MRSA, do NOT give if sulfa allergy is present. CAUSES nephrotoxicity, rash, other things
Metronidazoleanaorobe coverage, good for C.diff and UTIs, CAUSES encephalopathy, neuropathy, comes in IV andPO
Nitrofurantoingram positive plus GNRs, ONLY PO, do NOT give if CrCl<30, CAUSES discolored pee, GI upset, anemia, lactic acidosis
memorize