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Antibiotic Spectrum

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duckduckgoose's version from 2015-09-12 17:49

Penicillins

Question Answer
Natural Penicillins (Pen G, Pen V)Anaerobes, Strep, wimpy Gram neg.
Aminopenicillins (ampicillin, amoxicillin)Slightly worse for anaerobes, mainly wimpy Gram neg., Strep, some Enterococcus
Antistaph Penicillins (cloxacillin, oxacillin)Staph - cloxacillin for mastitis
Anti-pseudomonal penicllins (ticarcillin, pipercillin, carbenicillin)Pseudomonas (Gram neg enterics)
Beta-lactamase inhibitor combinations (clavulante/amoxicillin)Improved Staph coverage, Gram neg.
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Other Cell Wall Synthesis Inhibitors

Question Answer
1st gen cephalosporins (cephalexin, cefadroxil)Made for Staph, also Strep
2nd gen cephalosporins (cefoxitin, cefaclor)Gram + and Gram -
'3rd gen' cephalosporins (ceftiofur, cefpodoxime, cefovecin) Wimpy Gram neg.
ImipenemGram +, Gram -, anaerobes!
Glycopeptides (vancomycin)Gram +
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Protein Synthesis Inhibitors

Question Answer
Tetracyclines'Broad' Strep and wimpy Gram neg, unusual organisms
Aminoglycosides (gentamicin, amikacin)Aerobic Gram + & -, No anaerobes
Amphenicols Strep, wimpy Gram neg, ANAEROBES, some unusual organisms
MacrolidesAerobic Gram +, wimpy Gram -
Lincosamides (clindamycin, lincomycin)ANAEROBES, aerobic Gram + (Strep)
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Section 4

Question Answer
Blankoprim/SulfasWimpy Gram neg, Strep, Nocardia, UTIs
FluoroquinolonesStaph, Gram neg. aerobes
MetronidazoleANAEROBES only
RifampinMany Gram + aerobes
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