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Anti-nuclear antibodies associated with diseases

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oelomar's version from 2018-01-13 13:29

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Question Answer
Systemic lupus erythematosusdsDNA (as well as ANA, nRNP, Sm (Smith)).
Sjögren’s syndromeRo(SSA), La(SSB) (and ANA).
Myositis (polymyositis and dermatomyositis)Jo-1 (and ANA).
SCLE (subacute cutaneous lupus erythematosus)Ro(SSA), La(SSB).
CREST syndromeAnticentromere (and ANA).
Diffuse Systemic SclerosisScl-70 (and ANA).
Limited/localised/central Systemic SclerosisAnticentromere (and ANA) (note that limited systemic sclerosis is associated with CREST syndrome).
Mixed connective tissue disease (MCTD)nRNP.
Antiphospholipid syndromeAnticardiolipin antibody.
Granulomatosis with polyangiitis (GPA) (Wegener's granulamotosis)c-ANCA.
Eosinophilic granulomatosis with polyangiitis (EGPA) (Churg-strauss syndrome)p-ANCA.
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