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Amino Acid Breakdown Products

Updated 2009-02-15 23:11

Amino Acid Breakdown Products

These products can be converted into glucose or oxidized in the citric acid cycle.
Amino AcidsBreakdown Products
Asparagine, AspartateOxaloacetate
Tyrosine, Phenylalanine, AspartateFumarate
Isoleucine, Methionine, ValineSuccinyl CoA
Glutamate, Glutamine, Histidine, Proline, Arginineα-Keto-Glutarate
Isoleucine, Leucine, TryptophanAcetyl CoA
Leucine, Lysine, Phenylalanine, Tyrosine, TryptophanAcetoacetyl CoA
Alanine, Glycine, Cysteine, Serine, Threonine, TryptophanPyruvate
KetogenicProducts are Ketone Bodies: Acetyl CoA or Acetoacetyl CoA
GlucogenicProducts can be converted into Glucose
Leucine, LysinePurely Ketogenic
Isoleucine, Phenylalanine, Tryptophan, TyrosineBoth Ketogenic and Glucogenic
Most (14) of the Amino AcidsPurely Glucogenic


Reference: p.503 of Lubert Stryer's "Biochemistry" 3rd Edition, 1988, W. H. Freeman, New York (ISBN=0-7167-1843-X).

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