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Albin Drugs 6

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zomovefa's version from 2017-11-12 15:18

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Question Answer
Generalized anxiety short term txBenzodiazepines -> Increased frequency opening of chloride channels
B Blocker nonspecific drugina diabetic only symptoms you would see isSweating
Meperidine opiod contraindicated with other drugs such asSSRI's OR MAO'S -> blocks 5-HT reuptake
What drug worsens pheochromocytoma hypertension?Non selective b-blocker without giving an alpha blocker ->
WFW syndrome DOC to control V-fibProcainamide Class Ia
2-pamPralidoxime
DOC for H.PyloriOmeprazole, Clarithromycin and amoxicillin
Edema DOC that work synergistically with eachotherFurosemide+Hydrochlorothiazide
RanitidineInhibits the histamine H2 receptors of the parietal cells
Norepinephrine by itself causeshigh bp + low hr
Drugs that can cause acute or angle closure glaucomaDiphenydramine, amytriptyline, chlorpromazine, atropine, scopalamine, oxybutinin, tolterodine, tropicamide, meperidine Anti cholinergic
tolterodineBlockade of muscarinic acetycholine receptors-> decreases spasms of the bladder
Epinephrine reversalEpinephrine first increases bp -> Alpha antagonist given (phentolamine) -> Administration epinephrine causes decrease in BP
Doxycyline contraindicated inPregnancy
Thiazide can increaseAldosterone due to depletion of fluids and k from body leading to increased angiotensin II
DOC for Actinomyces israelliG+ anerobe bacteria -> Penicillin
Drugs that cause SIADHFluoxetine, TCA, MAOI's, antipsychotics, anti convulsants, anti neoplastics (Hyponatremia, Hypo Osmolarity,Impaired water excretion
Neuraminidase inhibitorsInhibits release or AKA maturation of virus
Metronidazole most common sxGI distress
Prostaglandins antagonist (Indomethacin) contraindicated in which kidney conditionNephrotic conditions due to constriction of afferent artery -> Lack of blood flow to kidney
Inducer drugs can decrease levels ofOral Contraceptives (Fat soluble) -> Amenorrhea-> Pregnant
Sumatriptan sxAssociated with development of ventricular arrhythmias, severe hypertension & serotonin syndrome Contraindicated in Prinzmental angina
Magnesium sulfate MOAInhibiting the release of acetylcholine at the motor end plate by inhibiting muscle via competitive inhibition of calcium
Chloroquine sxReactivation of psorasis & chloroquine induced retinopathy -> GIVE INSTEAD atovaquone
Pralidoxime for organophosphate poisoning treats byCorrecting excessive stimulation of nicotinic receptor by acetylcholine -> Treats muscle paralysis
ACE inhibitors contraindicated inRenal artery stenosis
ACE inhibitors VERY good inADPKD -> Because this condition produces high renin causing RAS activation so this drug inhibits Angiotenin I to Angiontenin II
What drugs are contraindicated in mysthaneia gravis pts?Aminoglycodsides, Chloroquine, PPP. Ciprofloxacin, Botulinm toxin ->
Diagnosis of MGEdrophonium
Pyridostigmine VS PhysostigmineMysthenia Gravis tx VS Atropine overdose/Glaucoma tx
Pyridostigmine/Neostigmine MOAAcetycholine estrase inhibitior -> preventing degradation of acetylcholine -> Increasing stimulation of the nicotinic acetylcholine receptors on skeletal muscle
Phenylphrine vs AtropineIncrease BP VS Increase BP& HR
Endometritis txGnRH analog
What drug antagonizes donepezil(cholinergic)?Anti-Cholinergic -> Inhibits parasympathetic
Parkinson tremor antimuscarinicTrihexyphenidyl -> Sympathetic
Zileutin VS LukastsArachnoid -> Leukotriens inhibited VS Leukotriene receptors blocked
Drugs that cause HYPERlipidemiaMetoprolol & Thiazides
BumetanIDELoop diuretic
Na K pump inhibitor at the distal convoluted tubule think of ACE inhibitor
Pt stops a medication because she ran out and now has a rebound hypertensionClonidine -> Important to slowly take them off this medication
Linezolid has weak MAO-I activityDO NOT GIVE with SSRIs.
Diphenyrdramine contraindicated iwth glaucoma pts due toAnti-Muscarnic effect -> Mydrasis
Quinidine is anINHIBITOR
Outdated Tetracyline(doxycyline) or Aminoglycoside, cisplatin, tenofovir, ifosfamide, valporic acid can causeFanconi Syndrome
Amiodarone treatsSVT, V-tach, V-fib, Refractory ventricular tachycardia
Acetylcholine + Hexamethonium causesA greater decrease in HR than ACH by itself because the baroreceptor itself is removed
Acetycholine + AtropineProduces virtually no effect because atropine is non selective cholinergic antagonist which prevents action of ACh
ACh stimulatesM2 receptors receptors in SA node causing decrease in HR
DOC to reverse the effects of vecuronium(Non depolarizing) & Stage II Succinylcholine effectsNeostigmine -> Acetylcholine esterase inhibitor
DOC for treating pts who have agranulocytosis from PTU or methimazole txB-blockers such as Propanolol & atenolol
Levothyroxine tx leads toDecreased TSH, Increased T4
Dihydroergotamine used for migraine sxRaynaud's phenomenon, Peripheral vascular ischemia
Bethanechol & Neostigmine used in postopertative paralytic ileusBethanechol muscarnic agonist VS Neostigmine Acetylcholinesterase inhibitor
Diabetic gastroparesis nausea vomiting postprandial fullness constipation txMetoclopramide
Rhabdomyolysis drug inducedStatins
Torsades pointes drug inducedQuinidine
Rebound hypertension drug inducedClonidine
Diabetes insipidus drug inducedLithium
Agranulocytosis drug inducedClozapine
Omeprazole increasesGastrin secretion by G cells due to lack of inhibition causing increase in gastric pH
Dronabinol and megestrol acetate dxstimulate appetite
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