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Adrenergic, Nicotinic, Muscarinic Receptors

rename
fatasone's version from 2017-09-30 01:21

Section

Question Answer
Eyealpha 1
Arrector Pilialpha 1
Respiratory Systembeta 2
Heartbeta 1
Arterioles and veinsalpha 1 and beta 2
GI tract wall motilityalpha 2, beta 2
GI sphinctersalpha 1
Urinary bladder-Detrusorbeta 2
Urinary bladder-Trigone and sphincteraplha 1
Kidney-Renin systembeta 1
Uterus-Pregnantbeta 2
Male sex organalpha 1, muscarinic (M3)
Presynaptic adrenergic neuronsalpha 2
Salivary Glandsbeta 1
Adipose tissuebeta 1
Vascular smooth muscle (skeletal)alpha 1 and beta 2
adrenal medeullanicotinic
post ganglionic neurons (PNS & SNS)nicotinic
all effector organs (PNS)muscarinic
sweat glandsmuscarinic (M3)
skeletal muscle motor end platenicotinic
lipolysisbeta 1 > beta 2, alpha 2 decrease lipolysis
MOA= IP3, DAG, ^Ca2+Muscarinic (M1), muscarinic (M3),
alpha 1
MOA= inhibition of adenyl cyclase, decrease cAMPalpha 2, (M2)
MOA= stimulation adenyl cyclase, ^cAMPbeta 1 and beta 2
MOA= opening Na+ & K+ channels, depolarizationnicotinic
memorize

 

Question Answer
alpha 1 functionconstriction, smooth muscle contraction, vasoconstriction, pupil dilation, ejaculation
alpha 2 functionrelaxation, decrease NE release, decrease insulin release
beta 1 functionincrease contraction, contractility, heart rate, cardiac output, lipolysis, renin secretion
beta 2 functiondilation (bronchodilation, bladder filling), smooth muscle relaxation, gluconeogenenis, glycogenolysis, insulin release, some lipolysis (mostly beta 1)
memorize