A Level Biology - Immunity Application Questions

saira's version from 2016-04-20 19:50


Question Answer
From your knowledge of cell-mediated immunity and lung structure suggest why humans infected by bird flu may sometimes die from suffocationBird flu infects the lungs, leading to massive overproduction of T cells. Accumulation of these cells may block the airways/fill the alveoli and cause suffocation
What is the purpose of adding detergent to the mixture of B cells and tumour cells?To break down the cell surface membrane of tumour cells allowing B cells and tumour cells to fuse. This will then allow the B cells to destroy the harmful tumour cells by producing antibodies.
When the detergent is added to the cells, the mixture is gently agitated. Suggest a reason why.To ensure the B cells and tumour cells repeatedly come into physical contact - This is essential if they are going to fuse and ensures maximum contact between both types of cell.
Why are cells from cancer tumours used to fuse with the B cells?Because B cells are SHORT LIVED and do not divide outside of the body. Tumour cells are LONG LIVED and divide outside of the body. Using both of them leads to long-lived B cells that can be grown outside of the body.
Some B cells and tumour cells fuse together. Suggest which other cells might also fuse together?--> B cells fuse with B cells.
--> Tumour cells fuse with Tumour cells.
How might an organisation that funds research DISHONESTLY INFLUENCE the outcome of that research?--> Present the findings in an incomplete/biased way.
--> Ignore unfavourable findings.
--> Withdraw funding for research that seems likely to find unfavourable findings.
--> Only fund research likely to produce favourable findings.