4-17-2105 #2

wumimimu's version from 2015-04-18 01:19


Question Answer
What are the elements of a DNR?No chest compressions, no defibrillation or IV drugs for terminal arrythmia, no intubation or mechanical rhythm
What is seen in histology of Psoriasis?Elongated rete ridges, parakertatosis, acanthosis, reduced/absent stratum granulosum, PMN's forming spongiotic clusters (Munroe microabscesses)
Which enzyme converts T4 to T3 in the peripheral tissues?Iodothyronine deiodinase
What does thyroid peroxodase do?oxidizes iodide, iodinates thyroglobulin, and couples 2 iodized tyrosine residues
What def is seen in Glanzmann thrombasthenia?Gp 2b/3a deficiency
What is abciximab used for?Percutaneous coronary intervention, acute coronary syndrome, and unstable angina
What is fibromyalgia characterized by?Widespread MSK pain, fatigue, neuropsych sx; >3 month
What is the treatment of fibromyalgia?Incremental aerobic exercise, also TCA's and SnRI's
Which cancer is associated with radical masectomy?Lymphangiosarcoma
What kind of skeletal abn does extramedullary hematopoiesis result in?Pathologic fractures, maxillary overgrowth and frontal bossing in children (chipmunk face)
What are the allosteric activators of phosphoylase kinaseUsually activated by Protein kinase A; but can be activated directly by calcium
Where does odansetron actPeripherally (5-HT receptors, presynaptic nerve terminals of vagus); also in the area postrema and the solitary nucleus and tract
What reactive hyperplasia?Benign enlargement of lymph node- polyclonal proliferation of lymphocytes
What suggests malignancy in lymph node?Monoclonal expansion of cells
What is the formula for volume of distribution?Amount of drug given/ amount in the plasma
What is the most common cause of hemorrhagic cystitis in children (esp males)Adenovirus
The mechanism of action of ethosuximide?Blocks T-type calcium channels in the thalamus
Mech of action of bisphosphonates?structural analogs of pyrophosphate (component of hydroxyapatite); they serve to make hydroxyapatite insoluble; also, they interfere with the action of osteoclasts
What happens to FRC in COPD?It increases!!!
What bacteria should you think of when you see "wool processing, animal hides, animal hair"B. Anthracis
What does pulmonary anthrax loook like?Myalgia, fever, malaise, and then hemorrhagic mediastinus (widended mediastinum on CXR), bloody plerual effusion, septic shock and death
What does b. anthracis look like when grow in culture?non-hemolyzing adherent colonies that grow in long chains that are known as medusa heads or serpentine
Where does tropheyema whipplei grow?Within macrophages; foamy macrophages packed with rod-shaped bacilli and PAS postive diatase resistant granules
What does carcinoid syndrome do the heart?Right sided endocardial fibrosis which may progress to pulmonic stenosis and/or restrictive cardiomyopathy
Where is actinomyces normally foundColon, mouth, vagina; also found in dental caries
What does actinomyces look like on microscopy?Branching filamentous pattern that exhibit sulfur granules
How do you treat an actinomyces infection?Penicillin
What size arteries does Kawasaki disease affect?Medium size arteries
What are the sx of kawasaki?Fever >5 days; cervical lymphadenopathy, bilateral conjunctivitis, mucositis, edema of hands and feet, desquamation of the fingertips, rash
What are the problems with short acting BZDs?Risk of physical dependence
What are the problems with long acting BZDs?Sedation (increased risk of falls
What are the short acting BZDs?Triazolam, Oxazepam, alprazolam
What are the long acting BZDS?Chlordiazepoxide, FLurazepam, diazepam, Clorazepate
How many myeloblasts are required to make the dx of AML?>/= 20%
What causes lacunar infarct?Ischemia of the small penetrating arteries that supply deep brain structures; hypertensive arteriolar sclerosis
What would posterior limb of internal capsule or basal pons lacunar stroke present with?Pure motor hemiparesis or Ataxia-hemiplegia syndrome
What would genu of internal capsule or basal pons stroke present as?Dysarthria-clumsy hand syndrome
What would ventroposterolateral or ventroposteromedial lacunar infarct present as?Pure sensory stroke
Cerebral amyloid angiopathy causes?Spontaneous lobar cortical hemorrhages
Charcot-Bouchard aneurysm rupture causes?hemorrhagic stroke involving deep brain structures
WIlson's disease, copper accumulates in what brain structure?Basal ganglia
What is the most common cause of kidney stones?Idiopathic hypercalciuria
What are hepatic adenomas strongly associated with?OCPs and anabolic steroids
What are hepatic angiosarcomas associated with?Expsosure to vinyl chloride, thorotrast, or arsenic
Hepatoblastoma?Most common liver neoplasm of children; associated with FAP or Beckwidth-Wiedemann syndrome
In which areas of the brain is atrophy most pronounced in alzheimers?Temperoparietal lobes and HIPPOCAMPUS
What does SAH look like on CTBlood filling all the ventricles (hyperattenuation)