2 Path- Developmental Disturbances

olola's version from 2017-02-09 02:14

Developmental Disturbances of the Oral Region and Tooth Structure

Question Answer
one of the most common dental abnormalities (2-10% prevalence)Hypodontia (max 3rd molar in 35% > max lateral > max premolar)
syndromes associated with hypodontia, oligodontia, anodontiaHereditary Ectodermal Dysplasia, Cranio-oculo-dental, Ehlers Syndromes, Hurler Type I, Otodental Dysplasia, Sturge-Weber
anodontia/oligodontia, lanugo hair, saddle nose, protuberant lips, heat intolerancehereditary ectodermal dysplasia recessive disorder
Hyperdontia is more common in what population?Asians
multiple supernumerary teeth are most common in which region of the mouth?mandibular premolar region
multiple supernumerary teeth is associated with what syndromes?Cleidocranial Dysplasia, Gardners syndrome, Downs syndrome
autosomal dominant, supernumerary teeth, Wormian bones, aplasia of claviclesCleidocranial dysplasia 1 in 1 million, defective gene 6p21
autosomal dominant, supernumerary teeth, osteomas, colon polyps, epidermoid cystsGardners syndrome (chromosome 5) prophylactic colectomy is tx due to high rate of malignancy
Taurodontism is associated with what syndromesAmelogenesis Imperfecta, Klinefelters, Down syndrome
supernumerary roots are most frequently seen in which teeth?mandibular premolars, mandibular canines
Hypercementosis is associated with what conditions?local factors (occlusal load), Pagets, Hyperpituitarism
hereditary disturbance- hard, opaque enamel, "snow-capped teeth"Hypomaturation type of AI (defect in maturation of enamel crystals)
hereditary disturbance- Normal thickness enamel that often chips and abrades easily, anterior open bite commonHypocalcified type of AI (defect in enamel mineralization)
opalescent teeth, "shell teeth"Dentinogenesis Imperfecta
classifications of Dentinogenesis ImperfectaType 1- associated with Osteogenesis Imperfecta, Type 2- not associated with OI, Type 3- rare and seen in Brandywine, MD
gnarled dentin, autosomal dominantDentin Dysplasia (Type I- radicular, Type II- coronal)
autosomal dominant, W-shaped short roots, pulp chambers horizontally oriented, periapical/periodontal disease commonType I Radicular Dentin Dysplasia
autosomal dominant, deciduous dentition are blue-gray, thistle-tube pulp chambers, pulp stonesType II Coronal Dentin Dysplasia
thin enamel, ghost teeth, NON-hereditaryRegional Odontodysplasia (ROD), etiology- local ischemia of affected teeth

Abnormalities of Soft Tissue

Question Answer
what defect is associated with Van der Woude Syndromeparamedial lip pit (autosomal dominant)
what defect is associated with Ascher syndromeDouble lip, Blepharochalasis, Nontoxic thyroid enlargement
possible etiology of hairy tonguesmoking, chromogenic bacteria, meds, food; more common in males
congenital causes of MacroglossiaDown syndrome, Beckwith-Wiedemann syndrome, MEN III, Idiopathic
secondary causes of Macroglossiatumors, amyloidosis, acromegaly, cretinism, myxedema
macroglossia, visceromegaly, gigantism, neonatal hypoglycemia, omphaloceleBeckwith-Widemann syndrome
Heterotopic development of sebaceous gland in mucosal surfaceFordyce granules
abnormal accumulation of fluid in the buccal mucosa epithelial cellsLeukoedema
autosomal dominant, thickened and folded oral mucosa, no tx, non-malignantWhite Sponge Nevus (Cannon Disease), mutation in mucosal keratin pair genes on chromosome 17, 12
dysphagia, dysphonia, dyspneaLingual Thyroid nodule females, dx by thyroid scanning, tx with excision

Abnormalities of Jaw and Face

Question Answer
hemihypertrophy was first reported by who?Meckle in 1822
etiology of hemifacial hypertrophyincreased neurovascular supply to affected area
associated anomalies with Hemifacial hypertorophymental retardation 20%, nevi, hemangioma, compensatory scoliosis, umbilical hernia, Wilm's tumor, hepatoblastoma, adrenocortical tumor
differential diagnosis for Hemifacial hypertrophyneoplasms (neurofibromatosis, sarcomas), masseter muscle hypertrophy, hemifacial atrophy (Romberg's hemiatrophy)
Scleroatrophic disfiguring process affecting one side of the face, due to localized sclerodermaHemifacial atrophy (Romberg's hemiatrophy)
at week ____, stomadeum is present- surrounded by the 1st arch5 weeks
what nutritional deficiency is associated with cleft lip and palateVitamin A deficiency
cleft lip and palate are most common in what population? least?most common- American Indians, least- Blacks
Cleft lip is more common in who? Cleft palate?Cleft lip- boys, Palate- girls
frequently associated anomalies with cleftcongenital heart disease, polydactylism, hydrocephalus, clubfoot, spina bifida